The evolution of eloquent located low-grade gliomas surgical approaches, their natural history and molecular classification

The evolution of eloquent located low-grade gliomas surgical approaches, their natural history and molecular classification

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Low-grade glioma is characterized by slow growth, infiltrative pattern through white matter tracts and progression to a malignant tumour type.The traditional classification is newly replaced by molecular stratification.This reorganisation gathers glioma with similar prognosis and treatment protocols.

The preferential location of Siemens KU20WVHF0G IQ-500 Built In F Wine Cooler Fits 21 Bottles Black New that tumour in eloquent areas constituted, over time, a real challenge regarding the best surgical approach.Because of the high risk of postoperative neurological deficits initially a more conservative management was adopted.Once with the development of preoperative and intraoperative functional assessment techniques, a higher degree of Classic Tee (White resection was possible in the limits of cortico-subcortical eloquence, being well known that this is a statistically significant factor for survival.

We present in this paper the natural evolution of low-grade glioma, their new molecular classification, prognostic factors and the various approach proposed for eloquent ones.